Keshan Disease Risk Increases With A Deficiency Of

Deficiency of this disease leads to pernicious anaemia megaloblastic anaemia methylmalonic acidemia etc. Ascorbic acid Vitamin C Deficiency results in Scurvy and the symptoms are bleeding gums swelling in joints and skin spots. 6413138 Indexed for MEDLINE MeSH terms. 3 The Third Affiliated Hospital Harbin Medical University 150 Haping Road 150081 Harbin Peoples Republic of China. Deficiency diseases such as white muscle disease it seems reasonable to suspect a connection between Se deficiency and Keshan disease. Nonexperimental and experimental studies have generated insufficient evidence for a role of selenium deficiency in human disease with the exception of Keshan disease a cardiomyopathy. In Asia and Africa dietary selenium deficiency is associated with a cardiomyopathy known as Keshan disease and an osteoarthropathy called Kashin-Beck disease.

Keshan disease KD is an endemic cardiomyopathy associated with selenium deficiency.

Trials were conducted to test the effectiveness of Se in the prevention of Keshan disease. Iodine deficiency is a lack of the trace element iodine an essential nutrient in the dietIt may result in metabolic problems such as goiter sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism which results in developmental delays and other health problemsIodine deficiency is an important global health issue especially. Keshan disease KD is an endemic cardiomyopathy with high fatality rates first reported in Keshan County in China in 1935 1. Deficiency of this disease leads to pernicious anaemia megaloblastic anaemia methylmalonic acidemia etc. Conversely recent randomized trials have indicated that selenium overexposure is positively associated with type. Nonexperimental and experimental studies have generated insufficient evidence for a role of selenium deficiency in human disease with the exception of Keshan disease a cardiomyopathy.

Keshan Disease Selenium Deficiency And The Selenoproteome Nejm

Keshan disease risk increases with a deficiency of. Selenium deficiency causes myopathy as a result of the depletion of selenium-associated enzymes which. Ascorbic acid Vitamin C Deficiency results in Scurvy and the symptoms are bleeding gums swelling in joints and skin spots. Deficiency diseases such as white muscle disease it seems reasonable to suspect a connection between Se deficiency and Keshan disease.

Nationwide KD has been reported in 2953 towns in 327 counties in 16 provinces municipalities and autonomous regions from northeast to southwest a band area. Pathology of Keshan disease. In addition to living in an area with soil low in selenium the following things can also increase your risk of selenium deficiency regardless of where you live.

Trials were conducted to test the effectiveness of Se in the prevention of Keshan disease. Overnutrition caused by overeating is also a form of malnutrition. Deficiency of this disease leads to pernicious anaemia megaloblastic anaemia methylmalonic acidemia etc.

To further clarify the correlation between GPx1 polymorphism and KD we. 3 The Third Affiliated Hospital Harbin Medical University 150 Haping Road 150081 Harbin Peoples Republic of China. Iodine deficiency is a lack of the trace element iodine an essential nutrient in the dietIt may result in metabolic problems such as goiter sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism which results in developmental delays and other health problemsIodine deficiency is an important global health issue especially.

Nationwide KD has been reported in 2953 towns in 327 counties in 16 provinces municipalities and autonomous regions from northeast to southwest a band area. 2 Institute of Keshan Disease Chinese Center for Endemic Disease Control Harbin Medical University 157 Baojian Road 150081 Harbin Peoples Republic of China. Nonexperimental and experimental studies have generated insufficient evidence for a role of selenium deficiency in human disease with the exception of Keshan disease a cardiomyopathy.

Conversely recent randomized trials have indicated that selenium overexposure is positively associated with type. Chronic selenium deficiency may also occur in individuals with malabsorption and long term selenium-deficient parenteral nutrition. Based on the above evidence it was concluded that selenium deficiency is the major cause of Keshan disease although other etiological factors could not be ruled out.

6413138 Indexed for MEDLINE MeSH terms. As elucidated by Alfred Sommer even mild subclinical deficiency can also be a problem as it may increase childrens risk of developing respiratory and diarrheal infections decrease growth rate slow bone development and decrease likelihood of survival from serious illness.

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It is not just the total amount of calories that matters but specific nutritional deficiencies such as vitamin A deficiency iron deficiency or zinc deficiency can also increase risk of death.

Several large population based intervention trials using oral administration of sodium selenite tablets showed significant reduction of Keshan disease incidence. Selenium deficiency causes myopathy as a result of the depletion of selenium-associated enzymes which. Keshan disease KD is an endemic cardiomyopathy with high fatality rates first reported in Keshan County in China in 1935. Extremely low Se levels in tissues of patients with Keshan disease were first reported in 1973 G. To further clarify the correlation between GPx1 polymorphism and KD we. It is not just the total amount of calories that matters but specific nutritional deficiencies such as vitamin A deficiency iron deficiency or zinc deficiency can also increase risk of death. Conversely recent randomized trials have indicated that selenium overexposure is positively associated with type. Nonexperimental and experimental studies have generated insufficient evidence for a role of selenium deficiency in human disease with the exception of Keshan disease a cardiomyopathy. Keshan disease KD is an endemic cardiomyopathy associated with selenium deficiency.

The greatest life-theatening risk to patients with protein S deficiency is a pulmonary embolism PE a deep vein thrombosis DVT that travels through the bloodstream and gets stuck in the lungs. As elucidated by Alfred Sommer even mild subclinical deficiency can also be a problem as it may increase childrens risk of developing respiratory and diarrheal infections decrease growth rate slow bone development and decrease likelihood of survival from serious illness. 3 The Third Affiliated Hospital Harbin Medical University 150 Haping Road 150081 Harbin Peoples Republic of China. In Asia and Africa dietary selenium deficiency is associated with a cardiomyopathy known as Keshan disease and an osteoarthropathy called Kashin-Beck disease. 2 Institute of Keshan Disease Chinese Center for Endemic Disease Control Harbin Medical University 157 Baojian Road 150081 Harbin Peoples Republic of China. Extremely low Se levels in tissues of patients with Keshan disease were first reported in 1973 G. To further clarify the correlation between GPx1 polymorphism and KD we.